Detection of a recombinant murine leukemia virus-related glycoprotein on virus-negative thymoma cells.
نویسندگان
چکیده
منابع مشابه
Presence of a novel recombinant murine leukemia virus-like glycoprotein on the surface of virus-negative C57BL lymphoma cells.
A line (BL/RLi2-NP) of C57BL mouse cells derived from an X-ray-induced thymic lymphoma was free of murine leukemia virus (MuLV) and expressed no viral antigens as determined by potent antisera reactive with group-specific determinants of MuLV p30 and gp70 polypeptides. However, using an antiserum directed against the gp70 of the VL-3 isolate of radiation leukemia virus, which reacted predominan...
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ابزارهای گوناگونی به منظور انتقال ژن به سلول های یوکاریوتی توسعه یافته اند، در میان آن ها، کارایی ویروس های rna دار متعلق به خانواده رتروویریده به دلیل الحاق پایدار ژنوم خود در کروموزوم های میزبان بالاتر است. ویروس لوکمی موش (mlv) شناخته شده ترین عضو جنس اورتورتروویرینا از گامارتروویروس ها است. ناقل ویروسی بر پایه mlv تنها قادر به بیان ژن های خارجی در سلول های در حال تقسیم میتوز می باشد، که بیا...
15 صفحه اولSelective host range restriction of goat cells for recombinant murine leukemia virus and feline leukemia virus type A.
We isolated a strain of normal goat fibroblasts which was uniquely selective in that it allowed the replication of xenotropic murine leukemia virus but not polytropic recombinant murine leukemia virus. In addition, feline leukemia virus type A replication was severely diminished in these goat cells, whereas feline leukemia virus type B and feline endogenous RD114-CCC viruses replicated efficien...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1981
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.78.3.1920